Dr. Aubrey de Gray's Conditions for Immortality

In this issue, I would like to talk about antioxidant research.

Antioxidant research may have the potential to lead to "immortality" in the future.

And as I mentioned in the previous article, "Can you achieve immortality if you prevent your body from rusting?", Dr. Aubrey de Gray of the U.S., who is an avid researcher of immortality, has given us seven conditions for immortality.

The Seven Conditions for Immortality

1. Eliminate mutations in nuclear chromosomes that cause cancer (prevention of cancer)

2. Eliminate mitochondrial mutations (prevent the cells from producing energy).

3. Reduce the amount of garbage inside the cells (prevent cardiovascular diseases)

4. Reduce extracellular debris (prevent Alzheimer's disease, which can cause blurred vision)

5. Maintain the formation of extracellular cross-links (maintain the body's elasticity, prevent wrinkles and high blood pressure)

6. Reduce the number of cells that should die but do not (prevent heart failure)

7. Preventing cell death (apoptosis)

These seven conditions are deeply related to antioxidant research.

But in this article, I will focus on the "cellular waste" in these seven conditions.

What is cellular waste?

What exactly does it mean to "reduce the amount of garbage inside and outside of cells" that is mentioned twice in these seven conditions? Furthermore, how can we reduce the amount of garbage inside and outside the cells?

First of all, this is the Nobel Prize in Physiology or Medicine in 2016, awarded to Japanese Professor Emeritus Yoshinori Ohsumi.

Professor Ohsumi's research is on a phenomenon called "autophagy".

In a nutshell, autophagy is the phenomenon of how cells clean up garbage that they do not originally need. This phenomenon is called "autophagy".

This phenomenon is very important.

If autophagy does not work properly, for example, in the case of Alzheimer's disease, amyloid-beta protein is stuck around the cells and cannot be cleaned up, thus causing Alzheimer's disease.

Another example is pancreatitis.

It is now known that pancreatitis is also caused by the inability of the pancreas to expel waste.

Autophagy is the process of disposing of garbage inside and outside cells, which is one of the conditions for immortality.

This is a very important item.

This research has finally seen the light of day after winning the Nobel Prize, and I believe that further research will be conducted in the future.

Professor Yoshinori Ohsumi, who was introduced here, is a Japanese doctor of biology born in 1945. He was a researcher at Tokyo Institute of Technology.

The Tokyo Institute of Technology has a detailed page on the subject, and I would like to introduce it to you.

The background of the research is also introduced, which is very interesting, so please read it.


Tokyo Institute of Technology: Tokyo Institute of Technology News "Autophagy - What is the research of Professor Emeritus Osumi who won the Nobel Prize?


Special page for Nobel Prize in Physiology or Medicine 2016